Luo, Shan

Research Assistant Professor

Division of Epidemiology and Biostatistics

  • PhD, MPH, BMed

Dr Luo received her Master’s degree in Public Health (with distinction) and PhD in Epidemiology and Biostatistics from the University of Hong Kong. Her research interest involves finding the determinants of major non-communicable diseases, as well as exploring the safety, validation and repositioning of drug targets with multi-omics data. Her recent work focuses on drug targets using data from the UK Biobank, "Children of 1997" birth cohort and publicly available data. 


  1. Research Output Prize, Li Ka Shing Faculty of Medicine, HKU, 2019-20,
  2. Mary Sun Medical Scholarship, HKU, 2019-20
  3. YS and Christabel Lung Postgraduate Scholarship, HKU, 2019-20
  4. Bau Tsu Zung Bau Kwan Yeu Hing Research and Clinical Fellowship, HKU, 2019-20
  5. YS and Christabel Lung Postgraduate Scholarship, HKU, 2018-19
Selected Publications

(*Denotes the corresponding author)

  1. Luo S, Liang Y, Wong THT, Schooling CM, Au Yeung SL. Identifying factors contributing to increased susceptibility to COVID-19 risk: a systematic review of Mendelian randomization studies. International Journal of Epidemiology. 2022 Apr 20:dyac076. [5-Year IF: 11.653; Public, Environment & Occupational Health: Ranked 16/210]
  2. Luo S, Au Yeung SL, Schooling CM. Assessing the linear and non-linear association of HbA1c with cardiovascular disease: a Mendelian randomisation study. Diabetologia 2021 Nov;64(11):2502-10. [5-Year IF: 10.617; Endocrinology & Metabolism: Ranked 11/146]
  3. Luo S,* Clarke SLN, Ramanan AV, Thompson S, Langefeld CD, Marion MC, Grom AA, Schooling CM, Gaunt TR, Au Yeung SL, Zheng J. Platelet glycoprotein Ib alpha chain as a putative therapeutic target for juvenile idiopathic arthritis: a Mendelian randomization study. Arthritis and Rheumatology. 2021 Apr; 73(4): 693-701 [5-Year IF: 12.681; Rheumatology: Ranked 4/34]
  4. Luo S, Schooling CM, Wong ICK, Au Yeung SL. Evaluating the impact of AMPK activation, a target of metformin on risk of cardiovascular diseases and cancer in the UK Biobank: a Mendelian randomization study. Diabetologia. 2020 Nov;63(11):2349-58. [5-Year IF: 10.617; Endocrinology & Metabolism: Ranked 16/210]
  5. Zheng J, Haberland V, Baird D, Walker V, Haycock P, Hurle MR, Gutteridge A, Erola P, Liu Y, Luo S, Robinson J, Richardson TG, Staley JR, Elsworth B, Burgess S, Sun BB, Danesh J, Runz H, Maranville JC, Martin HM, Yarmolinsky J, Laurin C, Holmes MV, Liu JZ, Estrada K, Santos R, McCarthy L, Waterworth D, Nelson MR, Smith GD, Butterworth AS, Hemani G, Scott RA, Gaunt TR. Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases. Nature Genetics. 2020 Oct; 52(10):1122-31. [5-Year IF: 39.321; Genetics & Heredity: Ranked 2/175]
  6. Luo S, Au Yeung SL, Zuber V, Burgess S, Schooling CM. The impact of genetically predicted red blood cell traits on venous thromboembolism, multivariable Mendelian randomization study using UK Biobank. Journal of the American Heart Association. 2020 Jul 21;9(14):e016771. [5-Year IF: 6.747; Cardiac & Cardiovascular Systems: Ranked 42/143]
  7. Au Yeung SL, Luo S, Schooling CM. The impact of GDF-15, a biomarker for metformin, on the risk of coronary artery disease, breast and colorectal cancer, and type 2 diabetes and metabolic traits: a Mendelian randomisation study. Diabetologia, 2019 Sept. 62(9): p. 1638-46 [5-Year IF: 11.653; Endocrinology & Metabolism: Ranked 16/210]
  8. Luo S, Au Yeung SL, Zhao J, Burgess S, Schooling CM. Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomization study in UK Biobank. BMJ. 2019 Mar 6; 364: l476. [5-Year IF: 64.449; Medicine, General & Internal: Rank 4/172] (Selected as Research Output Prize 2019-2020, Li Ka Shing Faculty of Medicine, The University of Hong Kong)
  9. Au Yeung SL, Luo S, Schooling CM. The Impact of Glycated Hemoglobin (HbA1c) on Cardiovascular Disease Risk: A Mendelian Randomization Study Using UK Biobank. Diabetes Care 2018 Sept;41(9):1991-97 [5-Year IF: 17.242; Endocrinology & Metabolism: Ranked 5/180]
  10. Schooling CM, Luo S, Johnson G. ADAMTS-13 activity and ischemic heart disease: a Mendelian randomization study. Journal of Thrombosis and Haemostasis. 2018 Nov;16(11):2270-5. [5-Year IF: 10.367; Hematology: Ranked 5/78]