Yu, Pak Hung Angus

YPHA
Post-doctoral Fellow

Division of Kinesiology

  • BEng (HKUST), Mphil (PolyU), MSc (CUHK), PhD (HKU)
phone 2831 5258
email phayu@hku.hk
pub med PubMed
Biography

Dr. Angus Yu has an academic background that spans multiple disciplines. Graduated with a Bachelor degree in Chemical and Bio-product Engineering from the Hong Kong University of Science and Technology in 2010, his science career began at the Hong Kong Polytechnic University, leading to the receipt of Master of Philosophy in 2013. He was also awarded a Master of Science degree in Genomics and Bioinformatics by the Chinese University of Hong Kong in 2016. Following the training in the School of Public Health at The University of Hong Kong, he received the title of Ph.D. in 2022. 

In concordant with his education, the research interest of Dr. Yu is diverse, whose research outputs span a spectrum of disciplines including molecular biology, metabolic health, sleep, and brain health. Currently, he is interested in investigating the effects of different exercise modalities on brain health, with an emphasis on mind-body exercise and conventional exercise.
Selected Publications
  1. Yu, A. P., Chin, E. C., Yu, D. J., Fong, D. Y., Cheng, C. P., Hu, X., Wei, G. X., & Siu, P. M. (2022). Tai Chi versus conventional exercise for improving cognitive function in older adults: a pilot randomized controlled trial. Sci Rep, 12(1), 8868. https://doi.org/10.1038/s41598-022-12526-5
  2. Siu, P. M.*, Yu, A. P.*, Chin, E. C., Yu, D. S., Hui, S. S., Woo, J., Fong, D. Y., Wei, G. X., & Irwin, M. R. (2021). Effects of Tai Chi or Conventional Exercise on Central Obesity in Middle-Aged and Older Adults : A Three-Group Randomized Controlled Trial. Ann Intern Med. https://doi.org/10.7326/M20-7014
  3. Siu, P. M.*, Yu, A. P.*, Tam, B. T., Chin, E. C., Yu, D. S., Chung, K. F., Hui, S. S., Woo, J., Fong, D. Y., Lee, P. H., Wei, G. X., & Irwin, M. R. (2021). Effects of Tai Chi or Exercise on Sleep in Older Adults With Insomnia: A Randomized Clinical Trial. JAMA Netw Open, 4(2), e2037199. https://doi.org/10.1001/jamanetworkopen.2020.37199
  4. Yu, A. P., Ugwu, F. N., Tam, B. T., Lee, P. H., Ma, V., Pang, S., Chow, A. S., Cheng, K. K., Lai, C. W., Wong, C. S., & Siu, P. M. (2020). Obestatin and growth hormone reveal the interaction of central obesity and other cardiometabolic risk factors of metabolic syndrome. Sci Rep, 10(1), 5495. https://doi.org/10.1038/s41598-020-62271-w
  5. Yu, A. P., Ugwu, F. N., Tam, B. T., Lee, P. H., Lai, C. W., Wong, C. S. C., Lam, W. W., Sheridan, S., & Siu, P. M. (2018). One Year of Yoga Training Alters Ghrelin Axis in Centrally Obese Adults With Metabolic Syndrome. Front Physiol, 9, 1321. https://doi.org/10.3389/fphys.2018.01321
  6. Yu, A. P., Ugwu, F. N., Tam, B. T., Lee, P. H., Lai, C. W., Wong, C. S. C., & Siu, P. M. (2018). Ghrelin Axis Reveals the Interacting Influence of Central Obesity and Hypertension. Front Endocrinol (Lausanne), 9, 534. https://doi.org/10.3389/fendo.2018.00534
  7. Yu, A. P.*, Tam, B. T.*, Lai, C. W., Yu, D. S., Woo, J., Chung, K. F., Hui, S. S., Liu, J. Y., Wei, G. X., & Siu, P. M. (2018). Revealing the Neural Mechanisms Underlying the Beneficial Effects of Tai Chi: A Neuroimaging Perspective. Am J Chin Med, 46(2), 231-259. https://doi.org/10.1142/S0192415X18500131
  8. Tam, B. T.*, Yu, A. P.*, Tam, E. W., Monks, D. A., Wang, X. P., Pei, X. M., Koh, S. P., Sin, T. K., Law, H. K. W., Ugwu, F. N., Supriya, R., Yung, B. Y., Yip, S. P., Wong, S. C., Chan, L. W., Lai, C. W., Ouyang, P., & Siu, P. M. (2018). Ablation of Bax and Bak protects skeletal muscle against pressure-induced injury. Sci Rep, 8(1), 3689. https://doi.org/10.1038/s41598-018-21853-5
  9. Yu, A. P., Pei, X. M., Sin, T. K., Yip, S. P., Yung, B. Y., Chan, L. W., Wong, C. S., & Siu, P. M. (2015). [D-Lys3]-GHRP-6 exhibits pro-autophagic effects on skeletal muscle. Mol Cell Endocrinol, 401, 155-164. https://doi.org/10.1016/j.mce.2014.09.031
  10. Yu, A. P., Tam, B. T., Yau, W. Y., Chan, K. S., Yu, S. S., Chung, T. L., & Siu, P. M. (2015). Association of endothelin-1 and matrix metallopeptidase-9 with metabolic syndrome in middle-aged and older adults. Diabetol Metab Syndr, 7, 111. https://doi.org/10.1186/s13098-015-0108-2
  11. Yu, A. P., Pei, X. M., Sin, T. K., Yip, S. P., Yung, B. Y., Chan, L. W., Wong, C. S., & Siu, P. M. (2014). Acylated and unacylated ghrelin inhibit doxorubicin-induced apoptosis in skeletal muscle. Acta Physiol (Oxf), 211(1), 201-213. https://doi.org/10.1111/apha.12263

Note: *Co-first author(s)

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