Zanin, Mark



  • PhD (Microbiology)
Prof Zanin received his PhD in Microbiology from Monash University in Melbourne, Australia and underwent postdoctoral training in influenza virology at St. Jude Children’s Research Hospital in Memphis, TN, USA with Dr. Robert Webster and Dr. Richard Webby. He subsequently established a research group at the State Key Laboratory of Respiratory Diseases in Guangzhou, China to study the emergence and transmission of zoonotic respiratory viruses. Prof Zanin’s research interests are the host and viral factors underlying transmission of respiratory viruses and interventions against viral respiratory diseases.
  1. Lei H, Ye F, Liu X, Huang Z, Ling S, Jiang Z, Cheng J, Huang X, Wu Q, Wu S, Xie Y, Xiao C, Ye D, Yang Z, Li Y, Leung N, Cowling B, He J, Wong SS, Zanin M (2020) SARS‐CoV‐2 environmental contamination associated with persistently infected COVID‐19 patients. Influenza and Other Respiratory Viruses 14:688
  2. Zanin M, DeBeauchamp J, Vangala G, Webby R, Husain M (2020) Histone Deacetylase 6 Knockout Mice Exhibit Higher Susceptibility to Influenza A Virus Infection. Viruses 12:728
  3. Zanin M, Wong SS, Barman S, Kaewborisuth C, Vogel P, Rubrum A, Darnell D, Marinova-Petkova A, Krauss S, Webby R, Webster R (2017) Molecular basis of mammalian transmissibility of avian H1N1 influenza viruses and their pandemic potential. Proceedings of the National Academy of Sciences of the United States of America 114:11217
  4. Zanin M, Kocer Z, Poulson R, Gabbard J, Howerth E, Jones C, Friedman K, Seiler J, Danner A, Kercher L, McBride R, Paulson J, Wentworth D, Krauss S, Tompkins S, Stallknecht D, Webster R (2017) The Potential for Low Pathogenic Avian H7 Influenza A Viruses to Replicate and Cause Disease in a Mammalian Model. Journal of Virology 91:e01934
  5. Zanin M, Duan S, Wong SS, Kumar G, Baviskar P, Collin E, Russell C, Barman S, Hause B, Webby R (2017) An amino acid in the stalk domain of N1 neuraminidase is critical for enzymatic activity. Journal of Virology 91:e00868
  6. Zanin M, Baviskar P, Webster R, Webby R. (2016) The interaction between respiratory pathogens and mucus. Cell Host & Microbe 19:159
  7. Kocer Z, Krauss S, Zanin M, Danner A, Gulati S, Jones J, Friedman K, Graham A, Forrest H, Seiler P, Air G, Webster R. (2015) Possible basis for the emergence of H1N1 viruses with pandemic potential from avian hosts. Emerging Microbes & Infections 4:e40
  8. Sadasivan S, Zanin M, O’Brien K, Schultz-Cherry S, Smeyne R. (2015) Induction of Microglia Activation after Infection with the Non-Neurotropic A/CA/04/2009 H1N1 Influenza Virus. PLoS One 10:e0124047
  9. Zanin M, Marathe B, Wong SS, Yoon SW, Collin E, Oshansky C, Jones J, Hause B, Webby R. (2015) Pandemic swine H1N1 influenza viruses with almost undetectable neuraminidase activity do not transmit via aerosols in ferrets and are inhibited by human mucus, but not swine mucus. Journal of Virology 89:5935
  10. Zanin M, Keck ZY, Rainey GJ, Lam CY, Boon AC, Rubrum A, Darnell D, Wong SS, Griffin Y, Xia J, Webster RG, Webby R, Johnson S, Foung S. (2015) An Anti-H5N1 Influenza Virus FcDART Antibody Is a Highly Efficacious Therapeutic Agent and Prophylactic against H5N1 Influenza Virus Infection. Journal of Virology 89:4549