PHRC seminar: Some Thoughts on Incidental Findings with Special Reference to Whole Genome Sequencing


Speaker: Dr Ron Zimmern

Date: November 15, 2013 (Friday)

Time: 12:15pm – 14:00pm

Venue: Seminar Room 2, G/F, Laboratory Block, Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong


The American College of Medical Genetics has recently produced recommendations on Whole Genome Sequencing and Whole Exome Sequencing (Genet Med 2013:15(7):565–574) in which they suggest that laboratories should analyse and report on variants in a pre-defined list of genes, whether or not related to the presenting complaint of the patient. This controversial recommendation has generated a lot of discussion within the genetics community, and has focused many to reflect on the nature of incidental findings in medical practice and how physicians might best deal with them. I intend to facilitate a discussion session on these recommendations. Those attending should have read the paper and be prepared to discuss its findings.