Dr Mateusz Aleksander Kudelko obtained his PhD degree from the University of Hong Kong, with a focus on dengue virus research and more precisely on dengue virus-host interaction. Following his degree he has built a track record spanning diverse research domains in both academic and industry settings. His research focused in the field of infectious and rare diseases, cancer and drug discovery. His previous experience at an immune-oncology startup, which was eventually acquired by BioNTech, combined with his subsequent role as Vice President of Drug Discovery, has provided him unique and valuable insights into translational research. His current work focuses on discovering a first-in-class dengue antiviral.

1. Kudelko M, Chen P, Tam V, Zhang Y, Kong OY, Sharma R, Au TYK, To MK, Cheah KSE, Chan WCW, Chan D. PRIMUS: Comprehensive proteomics of mouse intervertebral discs that inform novel biology and relevance to human disease modelling. Matrix Biol Plus. 2021 Dec;12:100082. doi: 10.1016/j.mbplus.2021.100082. IF=3.95, Q1 in Biochemistry.
2. Kudelko, M.; Yip, T.F.; Hei Law, G.C.; Lee, S.M.Y. Potential Beneficial Effects of Vitamin K in SARS-CoV-2 Induced Vascular Disease? Immuno 2021, 1, 17-29.  doi:10.3390/immuno1010003. IF=2.5, 122/183 in Immunology.
3. Tam V, Chen P, Yee A, Solis N, Klein T, Kudelko M, Sharma R, Chan WC, Overall CM, Haglund L, Sham PC, Cheah KSE, Chan D. DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics. Elife. 2020 Dec 31;9. doi: 10.7554/eLife.64940. IF=6,4 (2023), Q1 in Biochemistry.
4. Zhang Y, Xiong C, Kudelko M, Li Y, Wang C, Wong YL, Tam V, Rai MF, Cheverud J, Lawson HA, Sandell L, Chan WCW, Cheah KSE, Sham PC, Chan D. Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events. Matrix Biol. 2018 Sep;70:123-139. doi: 10.1016/j.matbio.2018.03.024. IF=4.8; 75/319 in Biochemistry & Mlc Biology.
5. Kudelko M, Sharma R, Cheah KS, Chan D. Comparison of proteomic datasets from hypertrophic chondrocytes in response to ER stress. Data Brief. 2016 Jun;7:449-51. doi: 10.1016/j.dib.2016.02.065.
6. Kudelko M, Chan CW, Sharma R, Yao Q, Lau E, Chu IK, Cheah KS, Tanner JA, Chan D. Label-Free Quantitative Proteomics Reveals Survival Mechanisms Developed by Hypertrophic Chondrocytes under ER Stress. J Proteome Res. 2016 Jan 4;15(1):86-99. doi: 10.1021/acs.jproteome.5b00537. IF=3.6, 14/86 in Biochemical Research Methods.
7. Li MY, Grandadam M, Kwok K, Lagache T, Siu YL, Zhang JS, Sayteng K, Kudelko M, Qin CF, Olivo-Marin JC, Bruzzone R, Wang PG. KDEL Receptors Assist Dengue Virus Exit from the Endoplasmic Reticulum. Cell Rep. 2015 Mar 10;10(9):1496-1507. doi: 10.1016/j.celrep.2015.02.021. IF=6.9, 44/204 in Cell Biology.
8. Kudelko M, Brault JB, Kwok K, Li MY, Pardigon N, Peiris JSM, Bruzzone R, Desprès P, Nal B, Wang PG. Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. J Biol Chem. 2012 Jan 2;287(1):767-777. doi: 10.1074/jbc.M111.270579. IF=3.9; 143/319 in Biochemistry & Mlc Biology.
9. Brault JB, Kudelko M, Vidalain PO, Tangy F, Desprès P, Pardigon N. The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication. Virology. 2011 Sep 1;417(2):369-78. doi: 10.1016/j.virol.2011.06.022. IF=2.4, 23/42 in Virology.
10. Wang PG, Kudelko M, Lo J, Siu LY, Kwok KT, Sachse M, Nicholls JM, Bruzzone R, Altmeyer RM, Nal B. Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. PLoS One. 2009 Dec 15;4(12):e8325. doi: 10.1371/journal.pone.0008325. IF=2.6, 44/135 in Multidisciplinary Sciences.