Featured Publications

2023

August - October

  1. The episodic resurgence of highly pathogenic avian influenza H5 virus
    Nature
    Xie R., Edwards K.M., Wille M., Wei X., Wong S.S., Zanin M., El-Shesheny R., Ducatez M., Poon L.L.M., Kayali G., Webby R.J. and Dhanasekaran V.
  2. Comparative antibody and cell-mediated immune responses, reactogenicity, and efficacy of homologous and heterologous boosting with CoronaVac and BNT162b2 (Cobovax): an open-label, randomised trial
    Lancet Microbe
    Leung N.H.L., Cheng S.M.S., Cohen C.A., Martín-Sánchez M., Au N.Y.M., Luk L.L.H., Tsang L.C.H., Kwan K.K.H., Chaothai S., Fung L.W.C., Cheung A.W.L., Chan K.C.K., Li J.K.C., Ng Y.Y., Kaewpreedee P., Jia J.Z., Ip D.K.M., Poon L.L.M., Leung G.M., Peiris J.S.M., Valkenburg S.A. and Cowling B.J.
  3. Development and application of influenza virus wastewater surveillance in Hong Kong
    Water Research
    Zheng X., Zhao K., Xu X., Deng Y., Leung K., Wu J.T., Leung G.M., Peiris J.S.M., Poon L.L.M and Zhang T.
  4. Wastewater genomic sequencing for SARS-CoV-2 variants surveillance in wastewater-based epidemiology applications
    Water Research
    Xu X., Deng Y., Ding J., Zheng X., Wang C., Wang D., Liu L., Gu H., Peiris J.S.M., Poon L.L.M., Zhang T.
  5. Long-term epidemiology and evolution of swine influenza viruses, Vietnam
    Emerging Infectious Diseases
    Cheung J., Bui A.N., Younas S., Edwards K.M., Nguyen H.Q., Pham N.T., Bui V.N., Peiris J.S.M. and Dhanasekaran V.
  6. Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk
    Journal of Internal Medicine
    Kim Y, Jang H, Wang M, Shi Q, Strain T, Sharp SJ, Yeung SLA, Luo S, Griffin S, Wareham NJ, Wijndaele K, Brage S.  
  7. Refining detection methods for emerging SARS-CoV-2 mutants in wastewater: A case study on the Omicron variants
    Science of the Total Environment
    Xu X., Deng Y., Ding J., Shi X., Zheng X., Wang D., Yang Y., Liu L., Wang C., Li S., Gu H., Poon L.L.M. and Zhang T.
January - July

  1. Risk of within-hotel transmission of SARS-CoV-2 during on-arrival quarantine in Hong Kong: an epidemiological and phylogenomic investigation
    Lancet Regional Health-Western Pacific
    Adam D.C., Martín-Sánchez M., Gu H., Yang B., Lin Y., Wu P., Lau E.H.Y., Leung G.M., Poon L.L.M. and Cowling B.J.
  2. Trajectories of sleep disturbance in cancer survivors during the first two years post-treatment
    Sleep
    Chan J, Ng DWL, Liao Q, Fielding R, Soong I, Chan KKL, Lee C, Ng AWY, Sze WK, Chan WL, Lee VHF, Lam WWT
  3. The influence of growth and sex hormones on risk of alzheimer's disease: a mendelian randomization study
    European Journal of Epidemiology
    Yeung C. H. C., Au Yeung S. L., Kwok M. K., Zhao J. V. and Schooling C. M.
  4. Can psychological distress account for the associations between COVID-19 vaccination acceptance and socio-economic vulnerability? 
    Applied Psychology: Health and Well-Being
    Yuan J, Dong M, Wong IOL, Cowing BY, Lam WWT, Ni MY, Liao Q.
  5. ALDH2 polymorphism, alcohol intake and the attributable burden of cancer in East Asia: systematic review, meta-analysis, and modelling study
    Annals of Epidemiology
    Ng CS, Ong XJ, Au M, Lau YH, Kwok HH, Quan J.
  6. Cigarettes, heated tobacco products and dual use: exhaled carbon monoxide, saliva cotinine and total tobacco consumed by Hong Kong tobacco users
    BMJ Tobacco Control
    Zhang X, Sun Y, Cheung YTD, Wang MP, Wu YS, Chak KY, Chen J, Leung LT, Lam TH, Ho SY.
  7. Resurgence of omicron BA. 2 in SARS-CoV-2 infection-naive Hong Kong
    Nature Communications
    Xie, R., Edwards, K.M., Adam, D.C., Leung, K.S., Tsang, T.K., Gurung, S., Xiong, W., Wei, X., Ng, D.Y., Liu, G.Y. and Krishnan, P.
  8. Within-host genetic diversity of SARS-CoV-2 lineages in unvaccinated and vaccinated individuals
    Nature Communications
    Gu H., Quadeer A.A., Krishnan P., Ng D.Y.M., Chang L.D.J., Liu G.Y.Z., Cheng S.M.S., Lam T.T.Y., Peiris J.S.M., McKay M.R. and Poon L.L.M.
  9. Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
    Emerging Infectious Diseases
    Hui K.P.Y., Ho J.C.W., Ng K.C., Cheng S.M.S., Sit K.Y., Au T.W.K., Poon L.L.M., Nicholls J.M., Peiris J.S.M. and Chan M.C.W.
  10. Diminishing benefits of urban living for children and adolescents' growth and development
    Nature
    NCD Risk Factor Collaboration (NCD-RisC) (Lam T.H., Ho D.S.Y., Leung G.M., Ni M.Y. and So H.K. are members in group authors)
  11. Reduced lean body mass: a potential modifiable contributor to the pathophysiology of heart failure
    European Heart Journal
    Diaz Canestro C., Ng H.F., Yiu K.H. and Montero Barril D.
  12. Association of growth patterns during infancy and puberty with lung function, wheezing and asthma in adolescents aged 17.5 years: evidence from ‘Children of 1997’ Hong Kong Chinese Birth Cohort
    International Journal of Epidemiology
    He B., Li A.M., Kwok M.K., Au Yeung S.L.R., Leung G.M. and Schooling C.M.
  13. Evaluating the role of non-alcoholic fatty liver disease in cardiovascular diseases and type 2 diabetes: a Mendelian randomization study in Europeans and East Asians
    International Journal of Epidemiology
    Au Yeung S.L.R., Borges M.C., Wong H.T., Lawlor D.A. and Schooling C.M.
  14. Effectiveness of BNT162b2 and CoronaVac COVID-19 vaccination against asymptomatic and symptomatic infection of SARS-CoV-2 omicron BA.2 in Hong Kong: a prospective cohort study
    Lancet Infectious Diseases
    Tsang N.N.Y., So H.C., Cowling B.J., Leung G.M. and Ip D.K.M.

  15. Monitoring school absenteeism for influenza-like illness surveillance: Systematic review and meta-analysis
    JMIR Public Health Surveillance
    Tsang T.K., Huang X., Guo Y., Lau E.H.Y., Cowling B.J. and Ip D.K.M.

  16. Overall and sex-specific effect of berberine for the treatment of dyslipidemia in adults: a systematic review and meta-analysis of randomized placebo-controlled trials
    Drugs
    Blais J.E., Huang X. and Zhao J.

  17. The city-wide full-scale interactive application of sewage surveillance programme for assisting real-time COVID-19 pandemic control - A case study in Hong Kong
    Science of the Total Environment
    Ng W.Y., Thoe W., Yang R., Cheung W.P., Chen C.K., To K.H., Pak K.M., Leung H.W., Lai W.K., Wong T.K., Lau T.K., Au K.W., Xu X.Q., Zheng X.W., Deng Y., Lau Y.K., To C.K., Peiris J.S.M., Leung G.M., Zhang T., Yang M., An W., Chen W., Wang C. and Chui H.K.

  18. Estimating the transmission dynamics of SARS-CoV-2 Omicron BF.7 in Beijing after the adjustment of zero-COVID policy in November - December 2022
    Nature Medicine
    Leung S.M.K., Lau E.H.Y., Wong C.K.H., Leung G.M. and Wu J.T.K.
  19. Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population
    Nature Medicine
    Lau J.J., Cheng M.S., Leung S.M.K., Lee C.K., Hachim A., Tsang C.H., Yam W.H., Chaothai S., Kwan K.H., Chai Y.H., Lo H.K., Mori M., Wu C., Valkenburg S.A., Amarasinghe G.K., Lau E.H.Y., Hui D.S.C., Leung G.M., Peiris J.S.M. and Wu J.T.K.
  20. Viral burden rebound in hospitalised patients with COVID-19 receiving oral antivirals in Hong Kong: a population-wide retrospective cohort study
    Lancet Infectious diseases
    Wong CKH, Lau KTK, Au ICH, Lau EHY, Poon LLM, Hung IFN, Cowling BJ, Leung GM. 
  21. Antibody and T cell responses against wild-type and Omicron SARS-CoV-2 after third-dose BNT162b2 in adolescents
    Signal Transduction and Targeted Therapy
    Mu X., Cohen C.A., Leung D., Rosa Duque J.S., Cheng S.M.S., Chung Y., Wong H.H.W., Lee A.M.T., Li W.Y., Tam I.Y.S., Lam J.H.Y., Lee D.H.L., Chan S.M., Tsang L.C.H., Chan K.C.K., Li J.K.C., Luk L.L.H., Chaothai S., Kwan K.K.H., Chu N.C., Mori M., Jeevan T., Kandeil A., Webby R.J., Tu W., Valkenburg S.A., Peiris J.S.M. and Lau Y.L.
  22. Genetic diversity and molecular epidemiology of Middle East respiratory syndrome coronavirus in dromedaries in Ethiopia, 2017-2020
    Emerging Microbes and Infections
    Zhou Z., Ali A., Walelign E., Demissie G.F., El Masry I., Abayneh T., Getachew B., Krishnan P., Ng D.Y.M., Gardner E., Makonnen Y., Miguel E., Chevalier V., Chu D.K., So R.T.Y., Von Dobschuetz S., Mamo G., Poon L.L.M. and Peiris J.S.M.

2022
  1. Serial intervals and incubation periods of the monkeypox virus clades
    Journal of Travel Medicine
    Wang S.Q., Zhang F.D., Yuan Z.L., Xu M.D., Wang Z., Gao C., Guo R.Z. and Du Z.
  2. Physical Activity Interventions to Alleviate Depressive Symptoms in Children and Adolescents: A Systematic Review and Meta-analysis
    JAMA Pediatrics
    Recchia F, Bernal JDK, Fong DY, Wong SHS, Chung PK, Chan DKC, Capio CM, Yu CCW, Wong SWS, Sit CHP, Chen YJ, Thompson WR, Siu PM.  
  3. Dose-response effects of exercise and caloric restriction on visceral adiposity in overweight and obese adults: a systematic review and meta-analysis of randomised controlled trials
    British Journal of Sports Medicine
    Recchia F, Leung CK, Yu AP, Leung W, Yu DJ, Fong DY, Montero D, Lee CH, Wong SHS, Siu PM.  
  4. Inferring time-varying generation time, serial interval, and incubation period distributions for COVID-19
    Nature Communications
    Chen D., Lau Y.C., Xu X.K., Wang L., Du Z., Tsang K.L.T., Wu P., Lau E.H.Y., Wallinga J., Cowling B.J. and Ali S.T.
  5. Real-world effectiveness of early molnupiravir or nirmatrelvir–ritonavir in hospitalised patients with COVID-19 without supplemental oxygen requirement on admission during Hong Kong's omicron BA.2 wave: a retrospective cohort study
    Lancet Infectious Diseases
    Wong C.K.H., Au C.H., Lau T.K.K., Lau E.H.Y., Cowling B.J. and Leung G.M.

  6. Lean body mass and the cardiovascular system constitute a female-specific relationship
    Science Translational Medicine
    Diaz-Canestro C, Pentz B, Sehgal A, Yang R, Xu A, Montero D.

  7. Comparative effectiveness of exercise, antidepressants and their combination in treating non-severe depression: a systematic review and network meta-analysis of randomised controlled trials
    British Journal of Sports Medicine
    Recchia F., Leung C.K., Chin C.Y.E., Fong D.Y.T., Montero Barril D., Cheng P.W.C., Yau S.Y. and Siu M.F.P.

  8. Pandemic fatigue impedes mitigation of COVID-19 in Hong Kong
    Proceedings of the National Academy of Sciences
    Du Z., Wang L.I.N., Shan S., Lam D., Tsang K.L.T., Xiao J., Gao H., Yang B., Ali S.T., Pei S., Fung I.C.H., Lau E.H.Y., Liao Q., Wu P., Meyers L.A., Leung G.M. and Cowling B.J.

  9. Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling, ambulatory patients with confirmed SARS-CoV-2 infection during the omicron wave in Hong Kong: an observational study
    The Lancet
    Wong C.K.H., AU C.H., Lau T.K.K., Lau E.H.Y., Cowling B.J. and Leung G.M.
  10. Vaccine effectiveness of one, two, and three doses of BNT162b2 and CoronaVac against COVID-19 in Hong Kong: a population-based observational study
    Lancet Infectious Diseases
    Mc Menamin M.E., Nealon J.A.P., Lin Y., Wong Y.T., Cheung K.H.J., Lau E.H.Y., Wu P., Leung G.M. and Cowling B.J.
  11. International risk of SARS-CoV-2 Omicron variant importations originating in South Africa
    Journal of Travel Medicine
    Bai Y., Du Z., Xu M., Wang L., Wu P., Lau E.H.Y., Cowling B.J. and Meyers L.A.
  12. Immunogenicity of a third dose of BNT162b2 to ancestral SARS-CoV-2 & Omicron variant in adults who received two doses of inactivated vaccine
    Clinical Infectious Diseases
    Leung NHL, Cheng SMS, Martín-Sánchez M, Au NYM, Ng YY, Luk LLH, Chan KCK, Li JKC, Leung YWY, Tsang LCH, Chaothai S, Kwan KKH, Ip DKM, Poon LLM, Leung GM, Malik Peiris JS, Cowling BJ.
  13. Reconstructing antibody dynamics to estimate the risk of influenza virus infection
    Nature Communications
    Tsang K.L.T., Perera R.A.P.M., Fang J., Wong Y.T., Shiu E.Y.C., So H.C., Ip D.K.M., Peiris J.S.M., Leung G.M., Cowling B.J. and Cauchemez S.T.

  14. Anti-pathogen stainless steel combating COVID-19
    Chemical Engineering Journal
    Liu L., Chin W.H., Yu P., Poon L.M.L. and Huang M.

  15. Epidemiology of infections with SARS-CoV-2 Omicron BA.2 variant, Hong Kong, January–March 2022
    Emerging Infectious Diseases
    Mesfin Y.M., Chen D., Bond H.S., Lin Y., Cheung K.H.J., Wong Y.T., Ali S.T., Lau E.H.Y., Wu P., Leung G.M. and Cowling B.J.

  16. Reproduction Numbers of SARS-CoV-2 Variants: A Systematic Review and Meta-analysis
    Clinical Infectious Diseases
    Du ZW, Liu CF, Wang CY, Xu LF, Xu MD, Wang L, Bai Y, Xu XK, Lau EHY, Wu P, Cowling BJ.
  17. Optimal timing of remdesivir initiation in hospitalized COVID-19 patients administered with dexamethasone
    Clinical Infectious Diseases
    Wong C.K.H., Lau T.K.K., Au C.H., Xiong X., Chung H.S., Lau E.H.Y. and Cowling B.J.
  18. Universal community nucleic acid testing for COVID-19 in Hong Kong reveals insights into transmission dynamics: a cross-sectional and modelling study
    Clinical Infectious Diseases
    Yang B., Tsang K.L.T., Gao H., Lau E.H.Y., Lin Y., Ho F., Xiao J., Wong Y.T., Adam D.C., Liao Q., Wu P., Cowling B.J. and Leung G.M.
  19. Natural Reassortment of Eurasian Avian-like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs, China
    Emerging Infectious Diseases
    Sun W., Cheng M.S., Lam N.T., Kwan T.C., Wong W.K., Lau H.K., Liu Y., Luk L.H., Li K.C., Gu H., Peiris J.S.M. and Poon L.M.L.
  20. Increased stability of SARS-CoV-2 Omicron variant over ancestral strain
    Emerging Infectious Diseases
    Chin A.W.H., Lai A.M.Y., Peiris J.S.M. and Poon L.M.L.
  21. Cost-effectiveness analysis of first-line treatment for chronic hepatitis B in China
    Clinical Microbiology and Infection
    Dai Z., Wong O.L., Xie C., Xu W., Xiang Y., Peng L. and Lau E.H.Y.
  22. Universal influenza vaccines are futile when benchmarked against seasonal influenza vaccines
    Lancet Infectious Diseases
    Valkenburg S.A. and Poon L.L.M.
  23. Maternal respiratory health and intrauterine exposure-driven birthweight: a two-sample Mendelian randomization study
    International Journal of Epidemiology
    He B., Kwok M.K., Chan I.I. and Schooling C.M.
  24. Remdesivir use and risks of acute kidney injury and acute liver injury among patients hospitalised with COVID-19: A self-controlled case series study
    Alimentary Pharmacology & Therapeutics
  25. Safety of two-dose COVID-19 vaccination (BNT162b2 and CoronaVac) in adults with cancer: a territory-wide cohort study
    Journal of Hematology & Oncology
    Kang W., Shami J.J.P., Yan V.K.C., Ye X., Blais J.E., Li X., Lee V.H.F., Chui C.S.L., Lai F.T.T., Wan E.Y.F., Wong C.K.H., Wong I.C.K. and Chan E.W.
  26. SARS-CoV-2 accessory proteins reveal distinct serological signatures in children
    Nature Communications
    Hachim A., Gu H., Kavian O., Mori M., Kwan M.Y.W., Chan W.H., Yau Y.S., Chiu S.S., Tsang O.T.Y., Hui D.S.C., Mok C.K.P., Ma F.N.L., Lau E.H.Y., Amarasinghe G.K., Qavi A.J., Cheng S.M.S., Poon L.L.M., Peiris J.S.M., Valkenburg S.A., Kavian N.
  27. Evaluation of RT-qPCR Primer-Probe Sets to Inform Public Health Interventions Based on COVID-19 Sewage Tests
    Environ Sci Technol
    Xu X, Deng Y, Zheng X, Li S, Ding J, Yang Y, On HY, Yang R, Chui HK, Yau CI, Tun HM, Chin AWH, Poon LLM, Peiris M, Leung GM, Zhang T.
  28. Genetic susceptibility, screen-based sedentary activities and incidence of coronary heart disease
    BMC Medicine
    Kim Y., Au Yeung S.L.R., Sharp S.J., Wang M., Jang H., Luo S., .Brage S. and Wijndaele K.
  29. Associations of face-to-face and non-face-to-face social isolation with all-cause and cause-specific mortality: 13-year follow-up of the Guangzhou Biobank Cohort study
    BMC Medicine
    Wang J., Zhang W., Jiang C., Zhu F., Jin Y.L., Cheng K.K., Lam T.H. and Xu L.
  30. Modeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India
    Nature Medicine
    Du ZW, Wang L, Pandey A, Lim WW, Chinazzi M, Piontti APY, Lau EHY, Wu P, Malani A, Cobey S, Cowling BJ.
  31. A randomized clinical trial using CoronaVac or BNT162b2 vaccine as a third dose in adults vaccinated with two doses of CoronaVac
    American Journal of Respiratory and Critical Care Medicine
    Mok C.K.P., Chen C., Yiu K., Chan T.O., Lai K.C., Ling K.C., Sun Y., Hui D.S., Cheng S.M.S, Peiris J.S.M.
  32. Remdesivir use and risks of acute kidney injury and acute liver injury among patients hospitalised with COVID-19: A self-controlled case series study
    Alimentary Pharmacology & Therapeutics
    Wong C.K.H., Au C.H., Cheng W.Y., Man K.C.K., Lau T.K.K., Mak L.Y., Lui S.L., Chung H.S., Xiong X., Lau E.H.Y. and Cowling B.J.
  33. Transmission of SARS-CoV-2 delta variant (AY.127) from pet hamsters to humans, leading to onward human-to-human transmission: a case study
    The Lancet
    Yen H.L., Sit T.H.C., Brackman C.J., Chuk S.S.Y., Gu H., Tam K.W.S., Law P.Y.T., Leung G.M., Peiris J.S.M. and Poon L.L.M.
  34. SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo
    Nature
    Hui K.P.Y., Ho J.C.W., Cheung M.C., Ng K.C., Ching R.H.H., Lai K.L., Kam T.T., Gu H., Sit K.Y., Hsin M.K.Y., Au T.W.K., Poon L.L.M., Peiris J.S.M., Nicholls J.M. and Chan M.C.W.
  35. Incorporating temporal distribution of population-level viral load enables real-time estimation of COVID-19 transmission
    Nature Communications
    Lin Y., Yang B.Y., Cobey S., Lau E.H.Y., Adam D.C., Wong J.Y., Bond H.S., Cheung J.K., Ho F., Gao H.Z., Ali S.T., Leung N.H.L., Tsang T.K., Wu P., Leung G.M. and Cowling B.J.
  36. Using genetics to assess the association of commonly used antihypertensive drugs with diabetes, glycaemic traits and lipids: a trans-ancestry Mendelian randomisation study
    Diabetologia
    Zhao J., Liu F.C., Schooling C.M., Li J.X., Gu D.F. and Lu X.F.
  37. Genomic epidemiology of SARS-CoV-2 under an elimination strategy in Hong Kong
    Nature Communications
    Gu H., Xie R., Adam D.C., Tsui L.H., Chu K.W., Chang L.D., Cheuk S.Y.S., Gurung S.G., Krishnan S.P., Ng Y.M.D., Liu Y., Kwong C.W.K., Cheng M.S., Edwards K.M., Leung S.M.K., Wu J.T.K., Tsang D.N.C., Leung G.M., Cowling B.J., Peiris J.S.M., Lam T.Y., Dhanasekaran V. and Poon L.M.L.
  38. Role of Epithelial–Endothelial cell interaction in the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
    Clinical Infectious Diseases
    Hui P.Y., Cheung M.C., LAI K.L., Ng K.C., Ho C.W.J., Peiris J.S.M., Nicholls J.M. and Chan M.C.W.
  39. Maternal respiratory health and intrauterine exposure-driven birthweight: a two-sample Mendelian randomization study
    International Journal of Epidemiology
    He B., Kwok M.K., Chan I.I. and Schooling C.M.
  40. Neutralizing antibodies against the SARS-CoV-2 Omicron variant following homologous and heterologous CoronaVac or BNT162b2 vaccination
    Nature Medicine
    Cheng SMS, Mok CKP, Leung YWY, Ng SS, Chan KCK, Ko FW, Chen C, Yiu K, Lam BHS, Lau EHY, Chan KKP, Luk LLH, Li JKC, Tsang LCH, Poon LLM, Hui DSC, Peiris M.
  41. A RCT Using CoronaVac or BNT162b2 Vaccine as a Third Dose in Adults Vaccinated with Two Doses of CoronaVac
    American Journal of Respiratory and Critical Care Medicine
    Mok CKP, Cheng SMS, Chen C, Yiu K, Chan TO, Lai KC, Ling KC, Sun Y, Peiris M, Hui DS.
  42. Influenza seasonality and its environmental driving factors in mainland China and Hong Kong
    Science of the Total Environment
    Ali S.T., Cowling B.J., Wong J.Y., Chen D., Shan S., Lau E.H.Y., He D., Tian L.W., Li Z. and Wu P.

 


2021
  1. Bell's palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study
    Lancet Infectious Diseases
    Wan Y.F.E., Chui S.L.C., Lai T.T.F., Chan E.W.Y., Li X., Yan K.C., Yu Q., Lam I.C.H., Chung K.C., Cowling B.J., Fong W.C., Lau A.Y.L., Mok V.C.T., Chan F.L.F., Lee C.K., Chan L.S.T., Lo D., Lau G.K.K., Hung F.N.I., Leung G.M. and Wong I.C.K.

  2. Ancestral sequence reconstruction pinpoints adaptations that enable avian influenza virus transmission in pigs
    Nature Microbiology
    Su W., Harfoot R., Su Y.C.F., DeBeauchamp J., Joseph U., Jayakumar J., Crumpton J.C., Jeevan T., Rubrum A., Franks J., Pascua P.N.Q., Kackos C., Zhang Y., Zhang M., Ji Y., Bui H.T., Jones J.C., Kercher L., Krauss S., Pleschka S., Chan M.C.W., Webster R.G., Wu C.Y., Van Reeth K., Peiris J.S.M., Webby R.J., Smith G.J.D. and Yen H.L.

  3. Universal community nucleic acid testing for COVID-19 in Hong Kong reveals insights into transmission dynamics: a cross-sectional and modelling study
    Clinical Infectious Diseases
    Yang B., Tsang K.L.T., Gao H., Lau E.H.Y., Lin Y., Ho F., Xiao J., Wong Y.T., Adam D.C., Liao Q., Wu P., Cowling B.J. and Leung G.M.

  4. Using Mendelian randomization study to assess the renal effects of antihypertensive drugs
    BMC Medicine
    Zhao J. and Schooling C.M.

  5. Understanding longevity in Hong Kong: a comparative study with long-living, high-income countries
    The Lancet Public Health
    Ni M.Y., Canudas-Romo V., Shi J., Flores F.P.C., Chow M.S.C., Yao X., Ho D.S.Y., Lam T.H., Schooling C.M., Lopez A.D., Ezzati M. and Leung G.M.

  6. Using secondary cases to characterize the severity of an emerging or re-emerging infection
    Nature Communications
    Tsang K.L.T., Wang C., Yang B., Cauchemez S.T. and Cowling B.J.

  7. Liveable residential space, residential density, and hypertension in Hong Kong: A population-based cohort study
    PLoS Medicine
    Sarkar C., Lai K.Y., Ni M.Y., Kumari S., Leung G.M. and Webster C.J.

  8. Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir
    ACS Central Science
    Lo H.S., Hui P.Y., Lai H.M., He X., Khan K.S.H., Kaur S., Huang J., Li Z.Q., Chan A.K., Cheung H.H., Ng K.C., Ho C.W.J., Chen Y.W., Ma B., Cheung P.M., Shin D., Wang K., Lee M.H., Selisko B., Eydoux C., Guillemot J.C., Canard B., Wu K.P., Liang P.H., Dikic I., Zuo Z., Chan F.K., Hui D.S.C., Mok V.C., Wong K.B., Mok C.K.P., Ko H., Aik W.S., Chan M.C.W. and Ng W.L.

  9. Role of Epithelial–Endothelial cell interaction in the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
    Clinical Infectious Diseases
    Hui P.Y., Cheung M.C., LAI K.L., Ng K.C., Ho C.W.J., Peiris J.S.M., Nicholls J.M. and Chan M.C.W.

  10. The role of cortisol in ischemic heart disease, ischemic stroke, type 2 diabetes, and cardiovascular disease risk factors: a bi-directional Mendelian randomization study
    BMC Medicine
    Kwok M.K., Kawachi I., Rehkopf D. and Schooling C.M.

  11. Effects of adjusting public health, travel, and social measures during the roll-out of COVID-19 vaccination: a modelling study
    The Lancet Public Health
    Leung S.M.K., Wu J.T.K. and Leung G.M.

  12. The joint association of physical activity and fine particulate matter exposure with incident dementia in elderly Hong Kong residents 
    Environment International
    Ran J., Zhang Y., Han L., Sun S., Zhao S., Shen C., Zhang X., Chan K.P., Lee R.S., Qiu Y. and Tian L.

  13. Mendelian Randomization Focused Analysis of Vitamin D on the Secondary Prevention of Ischemic Stroke
    Stroke
    Chan YH, Schooling CM, Zhao J, Au Yeung SL, Hai JJ, Thomas GN, Cheng KK, Jiang CQ, Wong YK, Au KW, Tang CS, Cheung CYY, Xu A, Sham PC, Lam TH, Lam KS, Tse HF.  

  14. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
    The Lancet
    Lam TH, Ho SY, So HK, et al (members of NCD Risk Factor Collaboration)

  15. Using Risk Stratification to Optimize Mammography Screening in Chinese Women
    JNCI Cancer Spectrum
    Leung K, Wu JT, Wong IO, Shu XO, Zheng W, Wen W, Khoo US, Ngan R, Kwong A, Leung GM.

  16. Optimal timing of remdesivir initiation in hospitalized COVID-19 patients administered with dexamethasone
    Clinical Infectious Diseases
    Wong C.K.H., Lau T.K.K., AU C.H., XIONG X., Chung H.S., Lau E.H.Y. and Cowling B.J.

  17. Cost-effectiveness analysis of first-line treatment for chronic hepatitis B in China
    Clinical Microbiology and Infection
    Dai Zonglin, Wong IOL, Xi Chan, Xu Wenxiong, Xiang Yu, Peng Liang, Lau Eric H. Y.

  18. Low vitamin D exposure and risk of nasopharyngeal carcinoma: Observational and genetic evidence from a multicenter case–control study
    Clinical Nutrition
    Mai Z., Ngan K.C.R., Ng W.T., Lin J., Kwong D.L.W., Yuen K.T., Lee C.K., Leung J.N.S., Ip D.K.M., Chan Y.H., Lee W.M.A., Lung M.L., Lam T.H. and Ho D.S.Y.  

  19. SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infection
    Nature Communications
    Cohen C.A., Li A.P.Y., Hachim A., Hui D.S.C., Kwan M.Y.W., Tsang O.T.Y., Chiu S.S., Chan W.H., Yau Y.S., Kavian N., Ma F.N.L., Lau E.H.Y., Cheng S.M.S., Poon L.L.M., Peiris M.. and Valkenburg S.A.

  20. Role of epithelial-endothelial cell interaction in the pathogenesis of SARS-CoV-2 infection
    Clinical infectious diseases
    Hui KP, Cheung MC, Lai KL, Ng KC, Ho JC, Peiris M, Nicholls JM, Chan MC.  

  21. Clinical improvement, outcomes, antiviral activity, and costs associated with early treatment with remdesivir for patients with COVID-19
    Clinical Infectious Diseases
    Wong C.K.H., Lau T.K.K., Au C.H., XIONG X., Lau E.H.Y. and Cowling B.J.

  22. Brief Advice, Nicotine replacement therapy Sampling and Active Referral (BANSAR) for expectant fathers who smoked: A Randomized Clinical Trial 
    JAMA Internal Medicine

    Luk TT, Lam TH, Leung WC, Leung K, Cheung KW, Kwa C, Siong K, Tang K, Lee K, Hsieh CJ, Wu Y, Li WHC, Wang MP.

  23. Development and validation of the CHIME simulation model to assess lifetime health outcomes of prediabetes and type 2 diabetes in Chinese populations: A modeling study
    PLoS Medicine
    Quan J., NG C.S., Kwok H.Y., Zhang A., Yuen Y.H., Choi C.H., Siu S.C., Tang S.Y., Wat N.M., Woo J., Eggleston K. and Leung G.M.

  24. Phenotypic and genetic characterization of MERS coronaviruses from Africa to understand their zoonotic potential
    Proceedings of the National Academy of Sciences of the USA (PNAS)
    Zhou Z., Hui K.P.Y., So R.T.Y., Lv H., Perera R.A.P.M., Chu D.K.W., Gelaye E., Oyas H., Njagi O., Abayneh T., Kuria W., Walelign E., Wanglia R., El Masry I., Von Dobschuetz S., Kalpravidh W., Chevalier V., Miguel E., Fassi-Fihri O., Trarore A., Liang W., Wang Y., Nicholls J.M., Zhao J., Chan M.C.W., Poon L.L.M., Mok C.K.P. and Peiris J.S.M.

  25. Serial intervals and case isolation delays for COVID-19: a systematic review and meta-analysis
    Clinical Infectious Diseases
    Ali S.T., Yeung A., Shan S., Wang L., Gao H., Du Z., Xu X., Wu P., Lau E.H.Y. and Cowling B.J.

  26. Smoking and nasopharyngeal cancer: individual data meta-analysis of six prospective studies on 334 935 men
    International Journal of Epidemiology
    Lin JH, Wen CP, Jiang CQ, Yuan, Chen CJ, Ho SY, Gao WN, Zhang WX, Wang RW, Chien YC, Xu L, Wu XF, Jin YL, Koh WP, Hsu WL, Zhu F, Wen C, Zhu T, Lee JH, Mai ZM, Lung ML, Lam TH.

  27. Virology, transmission, and pathogenesis of SARS-CoV-2
    BMJ
    Cevik M, Kuppalli K, Kindrachuk J, Peiris M. 

  28. Diagnostic performance of different sampling approaches for SARS-CoV-2 RT-PCR testing: a systematic review and meta-analysis
    The Lancet Infectious Diseases
    Tsang NNY, So HC, Ng KY, Cowling BJ, Leung GM, Ip DKM

  29. Assessing asymptomatic, pre-symptomatic and symptomatic transmission risk of SARS-CoV-2
    Clinical Infectious Diseases

    Wu P., Liu F., Chang Z., Lin Y., Ren M., Zheng C., Li Y., Peng Z., Qin Y., Yu J., Geng M., Yang X., Zhao H., Li Z., Zhou S., Ran L., Cowling B.J., Lai S., Chen Q., Wang L., Tsang K.L.T. and Li Z.

  30. Changing disparities in COVID-19 burden in the ethnically homogeneous population of Hong Kong through pandemic waves: an observational study
    Clinical Infectious Diseases

    Yang B, Wu P, Lau EHY, Wong JY, Ho F, Gao H, Xiao J, Adam DC, Ng TWY, Quan J, Tsang TK, Liao Q, Cowling BJ, Leung GM

  31. Case fatality risk of the first pandemic wave of novel coronavirus disease 2019 (COVID-19) in China
    Clinical Infectious Diseases
    Deng X., Yang J., Wang W., Wang X., Zhou J., Chen Z., Li J., Chen Y., Yan H., Zhang J., Zhang Y., Wang Y., Qiu Q., Gong H., Wei X., Wang L., Sun K., Wu P., Ajelli M., Cowling B.J., Viboud C. and Yu H.

  32. Long-term exposure to fine particulate matter and dementia incidence: A cohort study in Hong Kong
    Environmental Pollution
    Ran J., Schooling C.M., Han L., Sun S., Zhao S., Zhang X., Chan K.P., Guo F., Lee R.S., Qiu Y. and Tian L.

  33. T-cell responses to MERS coronavirus infection in people with occupational exposure to dromedary camels in Nigeria: an observational cohort study
    Lancet Infectious Diseases
    Mok CKP, Zhu A, Zhao J, Lau EHY, Wang J, Chen Z, Zhuang Z, Wang Y, Alshukairi AN, Baharoon SA, Wang W, Tan W, Liang W, Oladipo JO, Perera RAPM, Kuranga SA, Peiris M, Zhao J. 

  34. The transfer and decay of maternal antibodies against enterovirus A71, and dynamics of antibodies due to later natural infections in Chinese infants: a longitudinal, paired mother-neonate cohort study
    Lancet Infectious Diseases
    Wei X., Yang J., Gao L., Wang L., Liao Q., Qiu Q., Luo K., Yu S., Zhou Y., Liu F., Chen Q., Zhang J., Dai B., Yang H., Zhou J., Xing W., Chen X., He M., Ren L., Guo J., Luo L., Wu P., Chen Z., van Doorn H.R., Cauchemez S.T., Cowling B.J. and Yu H.

  35. Comparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study
    The Lancet Public Health
    Du Z., Pandey A., Bai Y., Fitzpatrick M.C., Chinazzi M., Pastore y Piontti A., Lachmann M., Vespignani A., Cowling B.J., Galvani A.P. and Meyers L.C.

  36. Intra-host variation and evolutionary dynamics of SARS-CoV-2 population in COVID-19 patients
    Genome Medicine
    Wang Y., Wang D., Zhang L., Sun W., Zhang Z., Chen W., Zhu A., Huang Y., Xiao F., Yao J., Gan M., Li F., Luo L., Huang X., Zhang Y., Wong S.S., Cheng X., Ji J., Ou Z., Xiao M., Li M., Li J., Ren P., Deng Z., Zhong H., Xu X., Song T., Mok C.K.P., Peiris J.S.M., Zhong N., Zhao J., Li Y., Li J. and Zhao J.

  37. Immunogenicity of standard, high-dose, MF59-adjuvanted, and recombinant-HA seasonal influenza vaccination in older adults
    NPJ Vaccines
    LI P.Y.A., Cohen C.A., Leung N.H.L., Fang J., Gangappa S., Sambhara S., Levine M.Z., Iuliano A.D., Perera R.A.P.M., Ip D.K.M., Peiris J.S.M., Thompson M.G., Cowling B.J. and Doak S.A.V.

  38. Neutralizing antibody titres in SARS-CoV-2 infections
    Nature Communications
    Lau E.H.Y., Tsang O.T.Y., Hui D.S.C., Kwan M.Y.W., Chan W.H., Chiu S.S.S., Ko L.W.R., Chan K.H., Cheng M.S., Perera R.A.P.M., Cowling B.J., Poon L.M.L. and Peiris J.S.M.

2020
  1. The transfer and decay of maternal antibodies against enterovirus A71, and dynamics of antibodies due to later natural infections in Chinese infants: a longitudinal, paired mother–neonate cohort study
    The Lancet Infectious Diseases
    Wei X., Yang J., Gao L., Wang L., Liao Q., Qiu Q., Luo K., Yu S., Zhou Y., Liu F., Chen Q., Zhang J., Dai B., Yang H., Zhou J., Xing W., Chen X., He M., Ren L., Guo J., Luo L., Wu P., Chen Z., van Doorn H.R., Cauchemez S.T., Cowling B.J. and Yu H.
  2. Clustering and superspreading potential of SARS-CoV-2 infections in Hong Kong
    Nature Medicine
    Adam D.C., Wu P., Wong Y.T., Lau E.H.Y., Tsang K.L.T., Cauchemez S.T., Leung G.M. and Cowling B.J.
  3. Pathogenesis and transmission of SARS-CoV-2 in golden hamsters
    Nature
    Sia S.F., Yan L., Chin W.H., Fung H.Y.K., Choy K.T., Wong A.Y., Wong A.Y., Perera R.A.P.M., Poon L.M.L., Nicholls J.M., Peiris J.S.M. and Yen H.
  4. Maternal antibodies against influenza in cord blood and protection against laboratory-confirmed influenza in infants
    Clinical Infectious Diseases
    Cowling B.J., Perera R.A.P.M., Fang J., Chu K.W., Hui P.W., Yeung A.P.C., Peiris J.S.M., Wong W.H.S., Shiu E.Y.C. and Chiu S.S.S.
  5. Comparative immunogenicity of several enhanced influenza vaccine options for older adults: A randomized, controlled trial
    Clinical Infectious Diseases
    Cowling BJ, Perera RAPM, Valkenburg SA, Leung NHL, Iuliano AD, Tam YH, Wong JHF, Fang VJ, Li APY, So HC, Ip DKM, Azziz-Baumgartner E, Fry AM, Levine MZ, Gangappa S, Sambhara S, Barr IG, Skowronski DM, Peiris JSM, Thompson MG
  6. ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection
    Nature Immunology
    Hachim A, Kavian N, Cohen CA, Chin AWH, Chu DKW, Mok CKP, Tsang OTY, Yeung YC, Perera RAPM, Poon LLM, Peiris JSM, Valkenburg SA
  7. The impact of the Syrian conflict on population well-being
    Nature Communications
    Cheung F., Kube A., Tay L., Diener E., Jackson J.J., Lucas R.E., Ni M.Y. and Leung G.M.
  8. Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions
    Science
    Ali ST, Wang L, Lau EHY, Xu XK, Du Z, Wu Y, Leung GM, Cowling BJ
  9. Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins
    Nature
    Lam TT, Shum MH, Zhu HC, Tong YG, Ni XB, Liao YS, Wei W, Cheung WY, Li WJ, Li LF, Leung GM, Holmes EC, Hu YL, Guan Y.
  10. Evolving epidemiology and transmission dynamics of coronavirus disease 2019 outside Hubei province, China: a descriptive and modelling study
    The Lancet Infectious Diseases
    Zhang J., Litvinova M., Wang W., Wang Y., Deng X., Chen X., Li M., Zheng W., Yi L., Chen X., Wu Q., Liang Y., Wang X., Yang J., Sun K., Longini I.M., Halloran M.E., Wu P., Cowling B.J., Merler S., Viboud C., Vespignani A., Ajelli M. and Yu H.
  11. Viral dynamics in mild and severe cases of COVID-19
    The Lancet Infectious Diseases
    Liu Y, Yan LM, Wan L, Xiang TX, Le A, Liu JM, Peiris M, Poon LLM, Zhang W.
  12. First-wave COVID-19 transmissibility and severity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment
    The Lancet
    Leung K, Wu JT, Liu D, Leung GM
  13. A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
    Science
    Yuan M, Wu NC, Zhu X, Lee CD, So RTY, Lv H, Mok CKP, Wilson IA.
  14. Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China
    Nature Medicine
    Wu J.T.K., Leung S.M.K., Bushman M., Kishore N., Niehus R., de Salazar P.M., Cowling B.J., Lipsitch M. and Leung G.M.
  15. Temporal dynamics in viral shedding and transmissibility of COVID-19
    Nature Medicine
    He X, Lau EHY, Wu P, Deng X, Wang J, Hao X, Lau YC, Wong JY, Guan Y, Tan X, Mo X, Chen Y, Liao B, Chen W, Hu F, Zhang Q, Zhong M, Wu Y, Zhao L, Zhang F, Cowling BJ, Li F, Leung GM
  16. Respiratory virus shedding in exhaled breath and efficacy of face masks
    Nature Medicine
    Nancy H. L. Leung, Daniel K. W. Chu, Eunice Y. C. Shiu, Kwok-Hung Chan, James J. McDevitt, Benien J. P. Hau, Hui-Ling Yen, Yuguo Li, Dennis K. M. Ip, J. S. Malik Peiris, Wing-Hong Seto, Gabriel M. Leung, Donald K. Milton, Benjamin J. Cowling.
  17. SARS-CoV-2 viral load in upper respiratory specimens of infected patients
    New England Journal of Medicine
    Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, Yu J, Kang M, Song Y, Xia J, Guo Q, Song T, He J, Yen HL, Peiris JSM, Wu J.
  18. Detection of influenza and other respiratory viruses in air sampled from a university campus: a longitudinal study
    Clinical Infectious Diseases
    Xie C., Lau E.H.Y., Yoshida T., Yu H., Wang X., Wu H., Wei J., Cowling B.J., Peiris J.S.M., Li Y. and Yen H.L.
  19. Avian influenza virus detection rates in poultry and environment at live poultry markets, Guangdong, China
    Emerging Infectious Diseases
    Cheng K.L., Wu J., Shen W.L., Wong A.Y.L., Guo Q., Yu J., Zhuang X., Su W., Song T., Peiris J.S.M., Yen H.L. and Lau E.H.Y.
  20. Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia
    New England Journal of Medicine
    Li Q.., Guan X., Wu P., Wang X., Zhou L., Tong Y., Ren R., Leung S.M.K., Lau E.H.Y., Wong Y.T., Xing X., Xiang N., Wu Y., Li C., Chen Q., Li D., Liu T., Zhao J.I.N.G., Liu M., Tu W., Chen C., Jin L., Yang R., Wang Q., Zhou S., Wang R., Liu H., Luo Y., Liu Y., Shao G., Li H., Tao Z., Yang Y., Deng Z., Liu B., Ma Z., Zhang Y., Shi G., Lam T.Y., Wu J.T.K., Gao G.F., Cowling B.J., Yang B., Leung G.M. and Feng Z.
  21. Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study
    The Lancet
    Wu JT, Leung K, Leung GM
  22. Depression and post-traumatic stress during major social unrest in Hong Kong: a 10-year prospective cohort study
    The Lancet
    Ni M.Y., Yao X., Leung S.M.K., Yau C.Y.S., Leung M.C., Lun K.Y.P., Flores F.P.C., Chang W.C., Cowling B.J. and Leung G.M.
  23. The association of early-life exposure to air pollution with lung function at ~17.5 years in the “Children of 1997” Hong Kong Chinese Birth Cohort
    Environment International
    He B., Huang J., Kwok M.K., Au Yeung S.L.R., Hui L.L., Li A.M., Leung G.M. and Schooling C.M.

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