Leung, Sze Man Kathy

Leung, Sze Man Kathy

LSMK
Research Assistant Professor

Division of Epidemiology and Biostatistics

  • PhD (HKU), MPhil (HKU), BS (Peking U)
Biography

Kathy Leung received her BS in Biological Sciences and Economics from School of Life Sciences and China Center for Economic Research at Peking University, MPhil and PhD from School of Public Health at The University of Hong Kong.

Kathy was initially a wet-bench trainee biochemist aiming to elucidate the signalling pathways of innate immunity against virus infections. Later she found her interest lies more in mathematics and statistics involved in biological processes. In recent years, her primary research is in mathematical modelling of a wide range of communicable and non-communicable diseases, such as influenza, MERS, hand-foot-and-mouth disease, HPV, cervical cancer, colorectal cancer and breast cancer. She also conducts epidemiological and economic evaluations of intervention strategies against communicable and non-communicable diseases, such as HFMD vaccination and breast cancer screening programmes. She was the core developer of HKU's first Massive Open Online Course (MOOC) Epidemics.

Website: https://sites.google.com/view/kathysleung/home?authuser=0

Google Scholar: https://scholar.google.com.hk/citations?hl=en&user=Ki1eg2UAAAAJ

Selected Publications
  1. Leung K, Wu JT, Liu D, Leung GM. (2020) First-wave COVID-19 transmissibility and severity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment. Lancet, 395(10233):1382-1393. DOI: 10.1016/S0140-6736(20)30746-7
    Impact factor: 60.392; No. of citations: 69;
    Ranking: 2/165, Q1 in Medicine, General & Internal
  2. Wu JT, Leung K, Bushman M, Kishore N, Niehus R, M de Salazar P, Cowling B J, Lipsitch M, Leung GM. (2020) Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China. Nature Medicine, 26(4):506-510. DOI: 10.1038/s41591-020-0822-7
    Impact factor: 36.13; No. of citations: 135;
    Ranking: 2/297, Q1 in Biochemistry & Molecular Biology; 3/195, Q1 in Cell Biology; 1/138, Q1 in Medicine, Research & Experimental
  3. Wu JT, Leung K, Leung GM. (2020) Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study. Lancet, 395(10225):689-697; DOI: 10.1016/S0140-6736(20)30260-9
    Impact factor: 60.392; No. of citations: 573;
    Ranking: 2/165, Q1 in Medicine, General & Internal
  4. Leung K, Lee CK, Lau EH, Lau CW, Wu JT. (2019) Assessing the impact of respiratory infections and weather conditions on donor attendance and blood inventory in Hong Kong. Vox sanguinis. DOI: 10.1111/vox.12745
    Impact factor: 2.347No. of citations: 0;
    Ranking: 46/76, Q3 in Hematology;
  5. Zheng Y, Jit M, Wu JT, Yang J, Leung K, Liao Q, Yu H.  (2017) Economic costs and health-related quality of life for hand, foot and mouth disease (HFMD) patients in China. PLoS One, 12(9), e0184266. DOI: 10.1371/journal.pone.0184266
    Impact factor:2.74No. of citations: 9;
    Ranking: 27/71, Q2 in Multidisciplinary Science
  6. Leung K*, Jit M*, Lau EHY, Wu JT. (2017) Social contact patterns relevant to the spread of respiratory infectious diseases in Hong Kong. Scientific Reports, 7(1), 7974. DOI: 10.1038/s41598-017-08241-1
    Impact factor:3.998No. of citations: 14;
    Ranking: 17/71, Q1 in Multidisciplinary Sciences;
  7. Leung K, Lipsitch M, Yuen KY, Wu JT. (2017) Monitoring the fitness of antiviral-resistant influenza strains during an epidemic: a mathematical modelling study. The Lancet Infectious Diseases, 17(3), 339-347. DOI: 10.1016/S1473-3099(16)30465-0
    Impact factor:24.446No. of citations: 6;
    Ranking: 1/93, Q1 in Infectious Diseases;
  8. Valkenburg SA, Zhang Y, Chan KY, Leung K, Wu JT, Poon LLM. (2016) Preexisting antibody-dependent cellular cytotoxicity–activating antibody responses are stable longitudinally and cross-reactive responses are not boosted by recent influenza exposure. Journal of Infectious Diseases, 214(8), 1159-1163. DOI: 10.1093/infdis/jiw346
    Impact factor:5.022No. of citations: 6;
    Ranking: 11/93, Q1 in Infectious Diseases; 26/135, Q1 in Microbiology; 39/158, Q1 in Immunology;
  9. Wu JT, Jit M, Zheng Y, Leung K, Xing W, Yang J, et al. (2016) Cost-effectiveness of routine pediatric enterovirus 71 vaccination in China. PLoS Medicine, 13(3), e1001975. DOI: 10.1371/journal.pmed.1001975
    Impact factor:10.5No. of citations: 25; 
    Ranking: 8/165, Q1 in Medicine, General & Internal;
  10. Yang J, Jit M, Leung KS, Zheng YM, Feng LZ, et al. (2015) The economic burden of influenza-associated outpatient visits and hospitalizations in China: a retrospective survey.Infectious Diseases of Poverty, 4(1), 1-11. DOI: 10.1186/s40249-015-0077-6
    Impact factor:3.067No. of citations: 23;
    Ranking: 40/93, Q2 in Infectious Diseases;
  11. Wu JT, Leung K, Perera RAPM, Chu DKW, Lee CK, Hung IFN, et al. (2014) Inferring influenza infection attack rate from seroprevalence data. PLoS Pathogens, 10(4), e1004054. DOI: 10.1371/journal.ppat.1004054
    Impact factor:6.218No. of citations: 30;
    Ranking: 3/37, Q1 in Virology; 4/39, Q1 in Parasitology; 19/135, Q1 in Microbiology;
  12. You F, Sun H, Zhou X, Sun W, Liang S, Zhai Z, & Jiang Z. (2009). PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. Nature immunology, 10(12), 1300-1308. DOI: 10.1038/ni.1815
    Impact factor:20.479No. of citations: 184;
    Ranking: 3/158, Q1 in Immunology;
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