Wu, Tsz Kei Joseph


Division of Epidemiology and Biostatistics

  • BS, PhD, FFPH

Professor Joseph Wu specializes in mathematical and statistical modelling of diseases and their interventions. His research aims are: (i) to develop useful analytics and strategies for disease control and prevention; and (ii) to translate his research findings into public health policy and practice for improving global health. He has worked on COVID-19, seasonal and pandemic influenza, hand-foot-and-mouth diseases, HPV, MERS, yellow fever, cervical cancer, colorectal cancer and breast cancer. He earned his PhD in Operations Research from MIT in 2003 and BS in Chemical Engineering from MIT in 1999.

He is the director of HKU's first Massive Open Online Courseware (MOOC) Epidemics which has had more than 16,000 people enrolled since its first launch in 2014. He is the director of the Croucher Summer Course Vaccinology for Public Health and Clinical Practice.

He is a member of the Center for Communicable Diseases Dynamics (CCDD) at the Harvard School of Public Health. He is an associate editor of the American Journal of Epidemiology and a Fellow of the Faculty of Public Health in the UK. He is a member of the WHO Advisory Committee on Immunization and Vaccines-related Implementation Research (IVIR-AC). He is a member of the Technical Working Group for the WHO Public Health Research Agenda for Influenza. He is a member of the MIT SOLVE Challenge Leadership Group and an SME advisor of MIT Innovation Node.


HKU Outstanding Young Researcher Award (2015)

HKU Research Output Prize (2015 and 2017)

HKU Li Ka Shing Faculty of Medicine Outstanding Research Output Award (2014, 2017, 2018 and 2019).

Selected Publications
  1. Wu JT, Leung K, Bushman M, Kishore N, Niehus R, M de Salazar P, Cowling B J, Lipsitch M, Leung GM. Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China. Nature Medicine. 2020.
    Impact factor: 36.13; No. of citations: 135;
    Ranking: 2/297, Q1 in Biochemistry & Molecular Biology; 3/195, Q1 in Cell Biology; 1/138, Q1 in Medicine, Research & Experimental
  2. Wu JT, Leung K, Leung GM. Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study. Lancet. 2020; S0140-6736(20)30260-9.
    Impact factor: 60.392; No. of citations: 573;
    Ranking: 2/165, Q1 in Medicine, General & Internal
  3. Wang L, Wu JT. Characterizing the dynamics underlying global spread of epidemics. Nature Communications 2018, 9(1):218.
    Impact factor: 12.121; No. of citations: 60;
    Ranking: 6/71, Q1 in Multidisciplinary Sciences
  4. Leung K, Lipsitch M, Yuen KY, Wu JT. Monitoring the fitness of antiviral-resistant influenza strains during an epidemic: a mathematical modelling study. The Lancet Infectious Diseases 2017, 17(3):339-347.
    Impact factor: 24.446; No. of citations: 6;
    Ranking: 1/93, Q1 in Infectious Diseases
  5. Wu JT, Peak CM, Leung GM, Lipsitch M: Fractional dosing of yellow fever vaccine to extend supply: a modelling study. Lancet 2016, 388(10062):2904-2911.
    Impact factor: 60.392; No. of citations: 32;
    Ranking: 2/165, Q1 in Medicine, General & Internal
  6. Wu JT, Jit M, Zheng Y, Leung K, Xing W, Yang J, Liao Q, Cowling BJ, Yang B, Lau EH et al: Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis. PLoS medicine 2016, 13(3):e1001975.
    Impact factor: 10.5; No. of citations: 25;
    Ranking: 8/165, Q1 in Medicine, General & Internal
  7. Wu JT, Ho A, Ma ES, Lee CK, Chu DK, Ho PL, Hung IF, Ho LM, Lin CK, Tsang T et al. Estimating Infection Attack Rates and Severity in Real Time during an Influenza Pandemic: Analysis of Serial Cross-Sectional Serologic Surveillance Data. PLoS medicine 2011, 8(10):e1001103.
    Impact factor: 10.5; No. of citations: 46;
    Ranking: 8/165, Q1 in Medicine, General & Internal
  8. Wu JT, Lee CK, Cowling BJ, Yuen KY. Logistical feasibility and potential benefits of a population-wide passive-immunotherapy program during an influenza pandemic. Proceedings of the National Academy of Sciences of the United States of America 2010, 107(7):3269-3274.
    Impact factor: 9.412; No. of citations: 26;
    Ranking: 8/71; Q1 in Multidisciplinary Sciences
  9. Wu JT, Leung GM, Lipsitch M, Cooper BS, Riley S. Hedging against antiviral resistance during the next influenza pandemic using small stockpiles of an alternative chemotherapy. PLoS medicine 2009, 6(5):e1000085.
    Impact factor: 10.5; No. of citations: 69;
    Ranking: 8/165, Q1 in Medicine, General & Internal
  10. Wu JT, Riley S, Fraser C, Leung GM: Reducing the impact of the next influenza pandemic using household-based public health interventions. PLoS medicine 2006, 3(9):e361.
    Impact factor: 10.5; No. of citations: 164;
    Ranking: 8/165, Q1 in Medicine, General & Internal