Wu, Tsz Kei Joseph

Division of Epidemiology and Biostatistics
Contact Information
Tel: 3917 6709
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Professor Joseph Wu specializes in mathematical and statistical modelling of diseases and their interventions. His research aims are: (i) to develop useful analytics and strategies for disease control and prevention; and (ii) to translate his research findings into public health policy and practice for improving global health. He has worked on influenza, hand-foot-and-mouth diseases, HPV, MERS, yellow fever, cervical cancer, colorectal cancer and breast cancer. He has published his research findings as the first or corresponding author in high-impact journals such as The Lancet, The Lancet Infectious Diseases, Nature Communications, PNAS, PLOS Medicine, etc. He earned his PhD in Operations Research from MIT in 2003 and BS in Chemical Engineering from MIT in 1999.

He is the director of HKU's first Massive Open Online Courseware (MOOC) Epidemics which has had more than 16,000 people enrolled since its first launch in 2014. He is the director of the Croucher Summer Course Vaccinology for Public Health and Clinical Practice.

He is a member of the Center for Communicable Diseases Dynamics (CCDD) at the Harvard School of Public Health. He is an associate editor of the American Journal of Epidemiology and a Fellow of the Faculty of Public Health in the UK. He is a member of the WHO Advisory Committee on Immunization and Vaccines-related Implementation Research (IVIR-AC). He is a member of the Technical Working Group for the WHO Public Health Research Agenda for Influenza. He is a member of the MIT SOLVE Challenge Leadership Group and an SME advisor of MIT Innovation Node.

He received the Outstanding Young Researcher Award from HKU in 2015, the Research Output Prize (Medicine) from HKU in 2015 and 2017, and the Outstanding Research Output Award from HKU Li Ka Shing Faculty of Medicine in 2014, 2017, 2018 and 2019.

HKU Scholars Hub: Wu, Joseph Tsz Kei

Wu Lab

Open Research and Contributor ID (ORCID): Wu, Joseph Tsz Kei


Selected Publications  (Pub Med Search)

  1. Wang L, Wu JT. Characterizing the dynamics underlying global spread of epidemics. Nature Communications, 9(1):218 (2018).
  2. Leung K, Lipsitch M, Yuen KY, Wu JT. Monitoring the fitness of antiviral-resistant influenza strains during an epidemic: a mathematical modelling study. The Lancet Infectious Diseases, 17(3): 339-347 (2017).
  3. Wu JT, Peak C, Leung GM & Lipsitch M. Fractional Dosing of Yellow Fever Vaccine to Extend Supply: A Modeling Study. The Lancet. doi: 10.1016/S0140-6736(16)31838-4 (2016).
  4. Wu JT, Jit, M, Zheng, Y, Leung, K, Xing, W, Yang, J, Liao, Q, Cowling, BJ, Yang, B, Lau, EH, Takahashi, S, Farrar, JJ, Grenfell, BT, Leung, GM & Yu, H. Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis. PLoS Medicine 13, e1001975, doi:10.1371/journal.pmed.1001975 (2016).
  5. Wu JT, Leung, K, Perera, RA, Chu, DK, Lee, CK, Hung, IF, Lin, CK, Lo, SV, Lau, YL, Leung, GM, Cowling, BJ & Peiris, JS. Inferring influenza infection attack rate from seroprevalence data. PLoS Pathogens 10, e1004054, doi:10.1371/journal.ppat.1004054 (2014).
  6. Yu H*, Wu JT*, Cowling BJ, Liao Q, Fang VJ, Zhou S, Wu P, Zhou H, Lau EHY, Guo D, Ni MY, Peng Z, Feng L, Jiang H, Luo H, Li Q, Feng Z, Wang Y, Yang W & Leung GM. Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study. The Lancet 383, 541-548, doi:10.1016/S0140-6736(13)61904-2 (2014).
  7. Wu JT, Ho, A, Ma, ES, Lee, CK, Chu, DK, Ho, PL, Hung, IF, Ho, LM, Lin, CK, Tsang, T, Lo, SV, Lau, YL, Leung, GM, Cowling, BJ & Peiris, JS. Estimating Infection Attack Rates and Severity in Real Time during an Influenza Pandemic: Analysis of Serial Cross-Sectional Serologic Surveillance Data. PLoS Medicine 8, e1001103, doi:10.1371/journal.pmed.1001103 (2011).
  8. Wu JT, Cowling, BJ, Lau, EH, Ip, DK, Ho, LM, Tsang, T, Chuang, SK, Leung, PY, Lo, SV, Liu, SH & Riley, S. School closure and mitigation of pandemic (H1N1) 2009, Hong Kong. Emerging Infectious Diseases 16, 538-541 (2010).
  9. Wu JT, Lee, CK, Cowling, BJ & Yuen, KY. Logistical feasibility and potential benefits of a population-wide passive-immunotherapy program during an influenza pandemic. Proceedings of the National Academy of Sciences of the United States of America 107, 3269-3274, doi:10.1073/pnas.0911596107 (2010).
  10. Wu JT, Ma, ES, Lee, CK, Chu, DK, Ho, PL, Shen, AL, Ho, A, Hung, IF, Riley, S, Ho, LM, Lin, CK, Tsang, T, Lo, SV, Lau, YL, Leung, GM, Cowling, BJ & Malik Peiris, JS. The infection attack rate and severity of 2009 pandemic H1N1 influenza in Hong Kong. Clinical Infectious Diseases 51, 1184-1191, doi:10.1086/656740 (2010).
  11. Wu JT, Leung, GM, Lipsitch, M, Cooper, BS & Riley, S. Hedging against antiviral resistance during the next influenza pandemic using small stockpiles of an alternative chemotherapy. PLoS Medicine 6, e1000085, doi:10.1371/journal.pmed.1000085 (2009).
  12. Wu JT, Riley, S, Fraser, C & Leung, GM. Reducing the impact of the next influenza pandemic using household-based public health interventions. PLoS Medicine 3, e361, doi:10.1371/journal.pmed.0030361 (2006).


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