Cheng, Mo Sheung Samuel

Research Officer

Division of Public Health Laboratory Sciences

  • BSc (HKPU), MPhil (HKU)

Mr Samuel Cheng received his MPhil degree in molecular virology investigating MERS-CoV from School of Public Health, the University of Hong Kong in 2016.

He has joined the Division of Public Health Laboratory Sciences for more than 10 years.  He is interested in viral surveillance in animals and human, development of molecular and serological diagnostic assays for infectious diseases, and genomic evolution and immune responses to emerging viruses.

He is now the leader of research teams investigating influenza viruses, MERS-CoV, SARS-CoV-2 and other emerging viruses in Prof. Peiris’ and Prof. Poon’s lab.
Selected Publications
  1. Cheng M.S., Mok C.K.P., Leung W.Y.Y., Ng S.S., Chan C.K.K., Ko F.W., Chen C., Yiu K., Lam B.H.S., Lau E.H.Y., Chan K.K.P., Luk L.H., Li K.C., Tsang C.H., Poon L.M.L., Hui D.S.C. and Peiris J.S.M., Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination, Nature Medicine. 2022, 28(3), 486-489.
  2. Cheng M.S., Mok C.K.P., Chan C.K.K., Ng S.S., Lam B.H.S., Luk L.H., Ko F.W., Chen C., Yiu K., Li K.C., Chan K.K.P., Tsang C.H., Poon L.M.L., Hui D.S.C. and Peiris J.S.M., SARS-CoV-2 Omicron variant BA.2 neutralisation in sera of people with Comirnaty or CoronaVac vaccination, infection or breakthrough infection, Hong Kong, 2020 to 2022, Eurosurveillance. 2022, 27.
  3. Cheng M.S., Mok C.K.P., Li K.C., Ng S.S., Lam B.H.S., Jeevan T., Kandeil A., Pekosz A., Chan C.K.K., Tsang C.H., Ko F.W., Chen C., Yiu K., Luk L.H., Chan K.K.P., Webby R.J., Poon L.M.L., Hui D.S.C. and Peiris J.S.M., Plaque-neutralizing antibody to BA.2.12.1, BA.4 and BA.5 in individuals with three doses of BioNTech or CoronaVac vaccines, natural infection and breakthrough infection, Journal of Clinical Virology. 2022, 156, 105273.
  4. Leung N.H.L., Cheng M.S., Martin Sanchez M., Au Y.M., Ng Y.Y., Luk L.H., Chan C.K.K., Li K.C., Leung W.Y.Y., Tsang C.H., Chaothai S., Kwan K.H., Ip D.K.M., Poon L.M.L., Leung G.M., Peiris J.S.M. and Cowling B.J., Immunogenicity of a third dose of BNT162b2 to ancestral SARS-CoV-2 & Omicron variant in adults who received two doses of inactivated vaccine, Clinical Infectious Diseases. 2022.
  5. Jia, J.Z., Tan, C.W., Cheng, S.M.S. et al. Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses. Nat Commun 13, 6285 (2022).
  6. Yen H., Sit T.H.C., Brackman C.J.B., Chuk S.H.I.R.L.E.Y.S., Gu H., Tam K.W.S., Law P.Y.T., Leung G.M., Peiris J.S.M., Poon L.M.L., Cheng M.S., Chang L.D., Krishnan S.P., Ng Y.M.D., Liu Y., Hui M.Y., Ho S.Y., Su W., Sia S.F., Choy K.T., Cheuk S.Y.S., Lau P.N., Tang W.Y., Koo C.T. and Yung L., Transmission of SARS-CoV-2 delta variant (AY.127) from pet hamsters to humans, leading to onward human-to-human transmission: a case study, The Lancet. 2022, 399(10329), 1070-1078.
  7. Sit H.C., Sun W., Tse C.N., Brackmen C.J., Cheng M.S., Tang W.Y., Cheung T.L., Peiris J.S.M. and Poon L.M.L., Novel Zoonotic Avian Influenza Virus A(H3N8) Virus in Chicken, Hong Kong, China, Emerging Infectious Diseases. 2022, 28(10), 2009-2015.
  8. SUN W., Cheng M.S., Lam N.T., Kwan T.C., Wong W.K., Lau H.K., Liu Y., Luk L.H., Li K.C., Gu H., Peiris J.S.M. and Poon L.M.L., Natural Reassortment of Eurasian Avian-like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs, China, Emerging Infectious Diseases. 2022, 28(7), 1509-1512.
  9. Chu K.W., Pan Y., Cheng M.S., Hui P.Y., Krishnan S.P., Liu Y., Ng Y.M.D., Wan K.C., Yang P., Wang Q., Peiris J.S.M. and Poon L.M.L., Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia, Clinical Chemistry. 2020, 66(4), 549-55.
  10. Chan M.S., Damdinjav B., Perera R.A.P.M., Chu K.W., Khishgee B., Enkhbold B., Poon L.L.M. and Peiris J.S.M., Absence of MERS-Coronavirus in Bactrian Camels, Southern Mongolia, November 2014, Emerging Infectious Diseases. 2015, 21(7), 1269-71.